Splash Biography

SCOTT HESTER, Student of Science and wrestler of Westies

Major: Johns Hopkins

College/Employer: Foundation Medicine, Tufts, Johns Hopkins

Year of Graduation: G

Brief Biographical Sketch:

Greetings humans!

Scott Hester here, formerly of Boston-Cambridge MA and currently of Tappahannock VA. I'm a Bioinformatics Analyst with a really great group of folks by way of Foundation Medicine, where I look at cancer patient tumor genomes to assess the accuracy/correctness for our various genomic tests (in a nutshell). In my spare time I enjoy wrestling a Westie named Wally, messing with computers, and watching my newfound favorite show: Antiques Roadshow. I've very much enjoyed teaching for Rainstorm/Splash in the past, and I'm thrilled to be back! 8)

-Scott

Past Classes

(Clicking a class title will bring you to the course's section of the corresponding course catalog)

S976: MCB000: Super-Resolution Fluorescence Imaging for Biological Discovery in Rainstorm Summer 2025 (Jul. 26 - 27, 2025)

We are living in an unprecedented age of biological imaging. Courtesy of the development of genetically-encoded fluorescent proteins and the incredible microscopes that exploit them, a vast wealth of biological dynamics have come to "light". This course will cover a range of really cool modern imaging techniques, in addition to a little history lesson on how we got here. Techniques such as Photoactivatable Localization Microscopy (PALM), Structured Illumination Microscopy (SIM), Lattice Light Sheets (with adaptive optics), IsoView, and 2-Photon microscopy will be discussed (In addition to a bunch of new stuff!). Fetal development, cancer metastasis, neuronal firing kinetics, and single-molecule tracking will be illustrated using these methods.

S864: MCB 000: Advances in Super-Resolution and Fluorescence Microscopy in Rainstorm Winter 2022 (Jan. 29 - 30, 2022)

We are living in an unprecedented age of biological imaging. Courtesy of the development of genetically-encoded fluorescent proteins and the microscopes that exploit them, a vast wealth of biological dynamics have come to "light". This course will cover a wide range of imaging techniques, with emphasis on those that function below the diffraction limit. After a brief synopsis of the history of microscopy, various techniques such as PALM, STORM, Lattice Light Sheet (with adaptive optics), IsoView, and 2-Photon microscopy will be discussed. Immune cell activity, fetal development, cancer metastasis, cellular endocytosis, neuronal firing kinetics, and single-molecule tracking will be illustrated using these methods.

S641: MCB 000: Advances in Super-Resolution and Fluorescence Microscopy in Rainstorm Spring 2021 (May. 15 - 16, 2021)

We are living in an unprecedented age of biological imaging. Courtesy of the development of genetically-encoded fluorescent proteins and the microscopes that exploit them, a vast wealth of biological dynamics have come to "light". This course will cover a wide range of imaging techniques, with emphasis on those that function below the diffraction limit. After a brief synopsis of the history of microscopy, various techniques such as PALM, STORM, SIM, Lattice Light Sheet (with adaptive optics), IsoView, and 2-Photon microscopy will be discussed. Fetal development, cancer metastasis, cellular endocytosis, dendritic arbor formation, neuronal firing kinetics, and single-molecule tracking will be illustrated using these methods.

S579: Advances in Super-Resolution Microscopy in Rainstorm Fall 2020 (Dec. 05 - 06, 2020)

We are living in an unprecedented age of biological imaging. Courtesy of the development of genetically-encoded fluorescent proteins and the microscopes that exploit them, a wealth of biological dynamics have come to "light". This course will cover a wide range of imaging techniques, with emphasis on those that function below the diffraction limit. After a brief synopsis of the history of microscopy, various techniques such as PALM, SIM, Lattice Light Sheet (with adaptive optics), IsoView, and 2-Photon microscopy will be discussed. Fetal development, cancer metastasis, cellular endocytosis, dendritic arbor formation, neuronal firing kinetics, and single-molecule tracking will be illustrated using these methods.